Articles Tagged With:
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Dengue Is Surging, Including in the Americas
Dengue is surging, and cases have been acquired in the United States, including in Puerto Rico and Florida.
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Beta-Lactam Antibiotics Administered via Prolonged Infusions Lead to Lower Mortality Risk Compared to Intermittent Infusions
In a systematic review and meta-analysis, the administration of beta-lactam antibiotics by prolonged infusions was associated with a significantly reduced risk of mortality at 90 days for critically ill patients with sepsis or septic shock as compared with intermittent infusions.
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Doxycycline for Onchocerciasis-Related Epilepsy?
Nodding syndrome is a form of pediatric encephalopathy with epilepsy that is associated with Onchocerca volvulus infection in children in Africa. While the pathogenesis is not known, doxycycline helps reduce severe seizures and death in children with nodding syndrome.
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Antibiotic De-Escalation Can Decrease the Development of Antibiotic Resistance in Gram-Negative Bacteria
A retrospective cohort study found that de-escalation of broad-spectrum beta-lactam agents in patients with sepsis significantly reduced the subsequent development of antimicrobial resistance in gram-negative bacteria isolated from clinical cultures.
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An Updated Review on Metabolic Regulation in the Alzheimer’s Brain: Type 3 Diabetes?
Diabetes is a strong risk factor for the development of Alzheimer's disease (AD) given the mitochondrial, vascular, and inflammatory modalities that contribute to its progression. Therefore, it is vital to understand the pathophysiology of these two diseases as they relate to insulin resistance and mitochondrial dysfunction. Exposing a metabolic relationship between these diseases can provide further understanding of metabolic health and how treatment of insulin resistance can decrease disease burden.
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Medical Students Feel Unprepared to Manage Financial Conflicts
Many medical students feel inadequately prepared to avoid negative influence from industry and feel inadequately educated on conflicts of interest, a recent study found.
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New Data Show Trends in Pediatric Ethics Consults
Pediatric ethics consultations are very infrequent and involve more diverse issues than ethics consults for adult patients. This makes it difficult to identify trends and changes.
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Diversity of Clinical Trial Participants Is Ethical Concern
Researchers soon will have additional guidance for increasing enrollment of participants from historically underrepresented populations. The U.S. Food and Drug Administration (FDA) has issued a draft guidance, Diversity Action Plans to Improve Enrollment of Participants from Underrepresented Populations in Clinical Studies.
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Stigmatizing Language in Patient Charts Linked to Diagnostic Errors
You have probably seen — and possibly even used — terms such as “difficult patient” or “drug-seeking” in medical charts. But did you ever wonder if stigmatizing language puts patients at risk for diagnostic error?
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Oncologists’ Ethical Concerns on Use of AI in Cancer Care
Most oncologists feel responsible for protecting patients from biased artificial intelligence tools, but few were confident in their ability to do so, a recent study found.